Magnesium and Your Internal Cell Clock

How Magnesium Regulates Your Metabolism and Your Internal Clocks

Your fluctuating levels of Magnesium, have a huge effect on your metabolism and your internal clock, researchers have found in a first of-its-kind study.

Experiments in three dominant types of organisms – human cells, algae, and fungi – found that in each individual case that magnesium levels in cells rise and fall in a roller-coaster of a daily cycle.

Scientists at the University of Edinburgh and the MRC laboratory for Molecular Biology in the UK found that this fluctuation is wildly important to sustain 24-hour internal clock regulation in cells.

They also concluded that magnesium has an enormous effect on your cells metabolism. For instance, how fast cells convert nutrients into energy throughout the course of a 24-hour span.

“Although the clinical relevance of magnesium in various tissues is beginning to garner more attention, how magnesium regulates our body’s internal clock and metabolism has simply not been considered before; until now.” Said John O’Neill from MRC Laboratory for Molecular Biology in Cambridge.

“The new discovery could lead to a whole range of benefits spanning human health to agricultural productivity,” O’Neill said.

This discovery is expected to like cells to whole body internal clocks, which influence daily cycles and life. Circadian Rhythms – sleeping and waking, body temperature, hormone release, and other bodily functions in humans are affected by these numerous “internal clocks”.

The Scientists used molecular analysis to find that magnesium concentration rose and fell over a 24 hour cycle in all cells. This impacts the cells’ internal clocks. Further studies concluded that magnesium levels work hand in hand with a cells’ ability to burn and produce energy. It’s been known for some time that magnesium is essential in converting food into energy, but these researchers were surprised to find that it controls how efficiently and when biological functions take place.

“Internal clocks are fundamental to all living things. They influence many aspects of health and disease in our own bodies, but equally in crop plants and micro-organisms,” said Gerben van Ooijen, from the University of Edinburgh.

“It is now essential to find out how these fundamentally novel observations translate to whole tissue or organisms, to make us better equipped to influence them in complex organisms for future medical and agricultural purposes.” Said van Ooijen, head of this study.


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